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Combined transplantation of the heart, lung, and liver may be indicated in patients with either end-stage respiratory failure complicated by advanced liver disease or end-stage liver failure complicated by advanced lung disease. A retrospective review of nine patients who underwent combined heart-lung-liver transplantation in Cambridge (1986-99) was carried out. The 1-year and 5-year actuarial survival was 56% and 42%, respectively. Combined heart-lung-liver transplantation is a feasible option for a few patients and has a 5-year survival similar to heart-lung transplantation but with a lower incidence of acute and chronic rejection.

Original publication

DOI

10.1016/S0140-6736(01)06003-2

Type

Journal article

Journal

Lancet

Publication Date

08/09/2001

Volume

358

Pages

812 - 813

Keywords

Adolescent, Adult, Aged, Cause of Death, Child, Female, Graft Survival, Heart Transplantation, Humans, Liver Transplantation, Lung Transplantation, Male, Middle Aged, Postoperative Period, Retrospective Studies, Survival Analysis, Treatment Outcome